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(De)stabilization of Alpha-Synuclein Fibrillary Aggregation by Charged and Uncharged Surfactants

Parkinson’s disease (PD) is the second most common neurodegenerative disorder. An important hallmark of PD involves the pathological aggregation of proteins in structures known as Lewy bodies. The major component of these proteinaceous inclusions is alpha (α)-synuclein. In different conditions, α-sy...

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Detalles Bibliográficos
Autores principales: Loureiro, Joana Angélica, Andrade, Stéphanie, Goderis, Lies, Gomez-Gutierrez, Ruben, Soto, Claudio, Morales, Rodrigo, Pereira, Maria Carmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624236/
https://www.ncbi.nlm.nih.gov/pubmed/34830391
http://dx.doi.org/10.3390/ijms222212509