Overcoming Microenvironment-Mediated Chemoprotection through Stromal Galectin-3 Inhibition in Acute Lymphoblastic Leukemia

Environmentally-mediated drug resistance in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) significantly contributes to relapse. Stromal cells in the bone marrow environment protect leukemia cells by secretion of chemokines as cues for BCP-ALL migration towards, and adhesion to, stroma. Str...

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Detalles Bibliográficos
Autores principales: Tarighat, Somayeh S., Fei, Fei, Joo, Eun Ji, Abdel-Azim, Hisham, Yang, Lu, Geng, Huimin, Bum-Erdene, Khuchtumur, Grice, I. Darren, von Itzstein, Mark, Blanchard, Helen, Heisterkamp, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624256/
https://www.ncbi.nlm.nih.gov/pubmed/34830047
http://dx.doi.org/10.3390/ijms222212167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624256/
https://www.ncbi.nlm.nih.gov/pubmed/34830047
http://dx.doi.org/10.3390/ijms222212167

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