Cargando…
Miscibility and Solubility of Caffeine and Theophylline in Hydroxypropyl Methylcellulose
As amorphization may improve the solubility and bioavailability of a drug substance, the aim of this work was to assess to what extent the crystallinity of caffeine (CAF) and theophylline (TF) can be reduced by homogenization with a polymeric excipient. To realize this purpose, the physical mixtures...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624303/ https://www.ncbi.nlm.nih.gov/pubmed/34834251 http://dx.doi.org/10.3390/pharmaceutics13111836 |