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Moderate Heat-Assisted Gene Electrotransfer as a Potential Delivery Approach for Protein Replacement Therapy through the Skin

Gene-based approaches for protein replacement therapies have the potential to reduce the number of administrations. Our previous work demonstrated that expression could be enhanced and/or the applied voltage reduced by preheating the tissue prior to pulse administration. In the current study, we uti...

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Detalles Bibliográficos
Autores principales: Edelblute, Chelsea, Mangiamele, Cathryn, Heller, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624362/
https://www.ncbi.nlm.nih.gov/pubmed/34834323
http://dx.doi.org/10.3390/pharmaceutics13111908