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Moderate Heat-Assisted Gene Electrotransfer as a Potential Delivery Approach for Protein Replacement Therapy through the Skin
Gene-based approaches for protein replacement therapies have the potential to reduce the number of administrations. Our previous work demonstrated that expression could be enhanced and/or the applied voltage reduced by preheating the tissue prior to pulse administration. In the current study, we uti...
Autores principales: | Edelblute, Chelsea, Mangiamele, Cathryn, Heller, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624362/ https://www.ncbi.nlm.nih.gov/pubmed/34834323 http://dx.doi.org/10.3390/pharmaceutics13111908 |
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