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Optimized In Silico Modeling of Drug Absorption after Gastric Bypass: The Case of Metformin

Bariatric surgery is an effective treatment for severe obesity and related comorbidities, such as type II diabetes. Gastric bypass surgery shortens the length of the intestine, possibly leading to altered drug absorption. Metformin, a first-line treatment for type II diabetes, has permeability-depen...

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Detalles Bibliográficos
Autores principales: Dahan, Arik, Porat, Daniel, Markovic, Milica, Zur, Moran, Kister, Olga, Langguth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624529/
https://www.ncbi.nlm.nih.gov/pubmed/34834288
http://dx.doi.org/10.3390/pharmaceutics13111873