Cargando…
Optimized In Silico Modeling of Drug Absorption after Gastric Bypass: The Case of Metformin
Bariatric surgery is an effective treatment for severe obesity and related comorbidities, such as type II diabetes. Gastric bypass surgery shortens the length of the intestine, possibly leading to altered drug absorption. Metformin, a first-line treatment for type II diabetes, has permeability-depen...
Autores principales: | Dahan, Arik, Porat, Daniel, Markovic, Milica, Zur, Moran, Kister, Olga, Langguth, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624529/ https://www.ncbi.nlm.nih.gov/pubmed/34834288 http://dx.doi.org/10.3390/pharmaceutics13111873 |
Ejemplares similares
-
The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
por: Markovic, Milica, et al.
Publicado: (2022) -
BCS Class IV Oral Drugs and Absorption Windows: Regional-Dependent Intestinal Permeability of Furosemide
por: Markovic, Milica, et al.
Publicado: (2020) -
Effect of Gastric Bypass Surgery on the Absorption and Bioavailability of Metformin
por: Padwal, Raj S., et al.
Publicado: (2011) -
Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development
por: Markovic, Milica, et al.
Publicado: (2020) -
Increased Paracetamol Bioavailability after Sleeve Gastrectomy: A Crossover Pre- vs. Post-Operative Clinical Trial
por: Porat, Daniel, et al.
Publicado: (2019)