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Connections between Immune-Derived Mediators and Sensory Nerves for Itch Sensation

Although histamine is a well-known itch mediator, histamine H(1)-receptor blockers often lack efficacy in chronic itch. Recent molecular and cellular based studies have shown that non-histaminergic mediators, such as proteases, neuropeptides and cytokines, along with their cognate receptors, are inv...

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Detalles Bibliográficos
Autores principales: Toyama, Sumika, Tominaga, Mitsutoshi, Takamori, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624544/
https://www.ncbi.nlm.nih.gov/pubmed/34830245
http://dx.doi.org/10.3390/ijms222212365