Design of a Quantitative LC-MS Method for Residual Toxins Adenylate Cyclase Toxin (ACT), Dermonecrotic Toxin (DNT) and Tracheal Cytotoxin (TCT) in Bordetella pertussis Vaccines

The antigens for acellular pertussis vaccines are made up of protein components that are purified directly from Bordetella pertussis (B. pertussis) bacterial fermentation. As such, there are additional B. pertussis toxins that must be monitored as residuals during process optimization. This paper de...

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Detalles Bibliográficos
Autores principales: Szymkowicz, Lisa, Gerard, Jeffery, Messham, Benjamin, Tam, Wai Wan Vivian, James, D. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624556/
https://www.ncbi.nlm.nih.gov/pubmed/34822547
http://dx.doi.org/10.3390/toxins13110763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624556/
https://www.ncbi.nlm.nih.gov/pubmed/34822547
http://dx.doi.org/10.3390/toxins13110763

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