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Comparison of PLA-Based Micelles and Microspheres as Carriers of Epothilone B and Rapamycin. The Effect of Delivery System and Polymer Composition on Drug Release and Cytotoxicity against MDA-MB-231 Breast Cancer Cells

Co-delivery of epothilone B (EpoB) and rapamycin (Rap) increases cytotoxicity against various kinds of cancers. However, the current challenge is to develop a drug delivery system (DDS) for the simultaneous delivery and release of these two drugs. Additionally, it is important to understand the rele...

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Detalles Bibliográficos
Autores principales: Jelonek, Katarzyna, Zajdel, Alicja, Wilczok, Adam, Kaczmarczyk, Bożena, Musiał-Kulik, Monika, Hercog, Anna, Foryś, Aleksander, Pastusiak, Małgorzata, Kasperczyk, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624627/
https://www.ncbi.nlm.nih.gov/pubmed/34834296
http://dx.doi.org/10.3390/pharmaceutics13111881