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Intranasal Zolmitriptan-Loaded Bilosomes with Extended Nasal Mucociliary Transit Time for Direct Nose to Brain Delivery

This study aimed at delivering intranasal zolmitriptan directly to the brain through preparation of bilosomes incorporated into a mucoadhesive in situ gel with extended nasal mucociliary transit time. Zolmitriptan-loaded bilosomes were constructed through a thin film hydration method applying Box–Be...

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Detalles Bibliográficos
Autores principales: El Taweel, Mai M., Aboul-Einien, Mona H., Kassem, Mohammed A., Elkasabgy, Nermeen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624645/
https://www.ncbi.nlm.nih.gov/pubmed/34834242
http://dx.doi.org/10.3390/pharmaceutics13111828