Reconstitution of human atlastin fusion activity reveals autoinhibition by the C terminus

ER network formation depends on membrane fusion by the atlastin (ATL) GTPase. In humans, three paralogs are differentially expressed with divergent N- and C-terminal extensions, but their respective roles remain unknown. This is partly because, unlike Drosophila ATL, the fusion activity of human ATL...

Descripción completa

Detalles Bibliográficos
Autores principales: Crosby, Daniel, Mikolaj, Melissa R., Nyenhuis, Sarah B., Bryce, Samantha, Hinshaw, Jenny E., Lee, Tina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624677/
https://www.ncbi.nlm.nih.gov/pubmed/34817557
http://dx.doi.org/10.1083/jcb.202107070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624677/
https://www.ncbi.nlm.nih.gov/pubmed/34817557
http://dx.doi.org/10.1083/jcb.202107070

Ejemplares similares