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Reconstitution of human atlastin fusion activity reveals autoinhibition by the C terminus
ER network formation depends on membrane fusion by the atlastin (ATL) GTPase. In humans, three paralogs are differentially expressed with divergent N- and C-terminal extensions, but their respective roles remain unknown. This is partly because, unlike Drosophila ATL, the fusion activity of human ATL...
Autores principales: | Crosby, Daniel, Mikolaj, Melissa R., Nyenhuis, Sarah B., Bryce, Samantha, Hinshaw, Jenny E., Lee, Tina H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624677/ https://www.ncbi.nlm.nih.gov/pubmed/34817557 http://dx.doi.org/10.1083/jcb.202107070 |
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