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Antidepressants and Circadian Rhythm: Exploring Their Bidirectional Interaction for the Treatment of Depression

Scientific evidence that circadian rhythms affect pharmacokinetics and pharmacodynamics has highlighted the importance of drug dosing-time. Circadian oscillations alter drug absorption, distribution, metabolism, and excretion (ADME) as well as intracellular signaling systems, target molecules (e.g.,...

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Detalles Bibliográficos
Autores principales: Silva, Soraia, Bicker, Joana, Falcão, Amílcar, Fortuna, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624696/
https://www.ncbi.nlm.nih.gov/pubmed/34834391
http://dx.doi.org/10.3390/pharmaceutics13111975