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Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan(®) (Semisolid) Formulation Using Human Skin and a Transdermal Diffusion Test Model
The effect of transdermal vehicle (Pentravan(®)) on skin permeability was examined for unmodified ibuprofen (IBU) and ion pairs of ibuprofen with new L-valine alkyl esters [ValOR][IBU]. The percutaneous permeation across the human skin and transdermal diffusion test model (Strat-M(®) membranes) of i...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624710/ https://www.ncbi.nlm.nih.gov/pubmed/34832210 http://dx.doi.org/10.3390/ma14226808 |