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Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan(®) (Semisolid) Formulation Using Human Skin and a Transdermal Diffusion Test Model

The effect of transdermal vehicle (Pentravan(®)) on skin permeability was examined for unmodified ibuprofen (IBU) and ion pairs of ibuprofen with new L-valine alkyl esters [ValOR][IBU]. The percutaneous permeation across the human skin and transdermal diffusion test model (Strat-M(®) membranes) of i...

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Detalles Bibliográficos
Autores principales: Ossowicz-Rupniewska, Paula, Nowak, Anna, Klebeko, Joanna, Janus, Ewa, Duchnik, Wiktoria, Adamiak-Giera, Urszula, Kucharski, Łukasz, Prowans, Piotr, Petriczko, Jan, Czapla, Norbert, Bargiel, Piotr, Markowska, Marta, Klimowicz, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624710/
https://www.ncbi.nlm.nih.gov/pubmed/34832210
http://dx.doi.org/10.3390/ma14226808