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Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Hypertension is a cardiovascular disease that needs long-term medication. Oral delivery is the most common route for the administration of drugs. The present research is to develop piperine self-nanoemulsifying drug delivery system (PE-SNEDDS) using glyceryl monolinoleate (GML), poloxamer 188, and t...

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Detalles Bibliográficos
Autores principales: Zafar, Ameeduzzafar, Imam, Syed Sarim, Alruwaili, Nabil K., Alsaidan, Omar Awad, Elkomy, Mohammed H., Ghoneim, Mohammed M., Alshehri, Sultan, Ali, Ahmed Mahmoud Abdelhaleem, Alharbi, Khalid Saad, Yasir, Mohd, Noorulla, Kaveripakkam M., Alzarea, Sami I., Alanazi, Abdullah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624913/
https://www.ncbi.nlm.nih.gov/pubmed/34835684
http://dx.doi.org/10.3390/nano11112920