Virus Infection, Genetic Mutations, and Prion Infection in Prion Protein Conversion

Conformational conversion of the cellular isoform of prion protein, PrP(C), into the abnormally folded, amyloidogenic isoform, PrP(Sc), is an underlying pathogenic mechanism in prion diseases. The diseases manifest as sporadic, hereditary, and acquired disorders. Etiological mechanisms driving the c...

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Detalles Bibliográficos
Autores principales: Hara, Hideyuki, Sakaguchi, Suehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624980/
https://www.ncbi.nlm.nih.gov/pubmed/34830321
http://dx.doi.org/10.3390/ijms222212439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624980/
https://www.ncbi.nlm.nih.gov/pubmed/34830321
http://dx.doi.org/10.3390/ijms222212439

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