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Virus Infection, Genetic Mutations, and Prion Infection in Prion Protein Conversion
Conformational conversion of the cellular isoform of prion protein, PrP(C), into the abnormally folded, amyloidogenic isoform, PrP(Sc), is an underlying pathogenic mechanism in prion diseases. The diseases manifest as sporadic, hereditary, and acquired disorders. Etiological mechanisms driving the c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624980/ https://www.ncbi.nlm.nih.gov/pubmed/34830321 http://dx.doi.org/10.3390/ijms222212439 |