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Copolymer Coatings for DNA Biosensors: Effect of Charges and Immobilization Chemistries on Yield, Strength and Kinetics of Hybridization

The physical–chemical properties of the surface of DNA microarrays and biosensors play a fundamental role in their performance, affecting the signal’s amplitude and the strength and kinetics of binding. We studied how the interaction parameters vary for hybridization of complementary 23-mer DNA, whe...

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Detalles Bibliográficos
Autores principales: Vanjur, Luka, Carzaniga, Thomas, Casiraghi, Luca, Zanchetta, Giuliano, Damin, Francesco, Sola, Laura, Chiari, Marcella, Buscaglia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625010/
https://www.ncbi.nlm.nih.gov/pubmed/34833198
http://dx.doi.org/10.3390/polym13223897