Next-Generation Computationally Designed Influenza Hemagglutinin Vaccines Protect against H5Nx Virus Infections

H5N1 COBRA hemagglutinin (HA) sequences, termed human COBRA-2 HA, were constructed through layering of HA sequences from viruses isolated from humans collected between 2004–2007 using only clade 2 strains. These COBRA HA proteins, when expressed on the surface of virus-like particles (VLP), elicited...

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Detalles Bibliográficos
Autores principales: Nuñez, Ivette A., Huang, Ying, Ross, Ted M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625041/
https://www.ncbi.nlm.nih.gov/pubmed/34832509
http://dx.doi.org/10.3390/pathogens10111352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625041/
https://www.ncbi.nlm.nih.gov/pubmed/34832509
http://dx.doi.org/10.3390/pathogens10111352

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