Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding

The novel 1,2,3-triazolyl-appended N- and O-heterocycles containing amidine 4–11 and amidoxime 12–22 moiety were prepared and evaluated for their antiproliferative activities in vitro. Among the series of amidine-substituted heterocycles, aromatic diamidine 5 and coumarine amidine 11 had the most po...

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Detalles Bibliográficos
Autores principales: Maračić, Silvija, Grbčić, Petra, Shammugam, Suresh, Radić Stojković, Marijana, Pavelić, Krešimir, Sedić, Mirela, Kraljević Pavelić, Sandra, Raić-Malić, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625065/
https://www.ncbi.nlm.nih.gov/pubmed/34834151
http://dx.doi.org/10.3390/molecules26227060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625065/
https://www.ncbi.nlm.nih.gov/pubmed/34834151
http://dx.doi.org/10.3390/molecules26227060

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