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The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation

A growing number of studies indicate that mRNAs and long ncRNAs can affect protein populations by assembling dynamic ribonucleoprotein (RNP) granules. These phase-separated molecular ‘sponges’, stabilized by quinary (transient and weak) interactions, control proteins involved in numerous biological...

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Detalles Bibliográficos
Autores principales: Lyonnais, Sébastien, Sadiq, S. Kashif, Lorca-Oró, Cristina, Dufau, Laure, Nieto-Marquez, Sara, Escribà, Tuixent, Gabrielli, Natalia, Tan, Xiao, Ouizougun-Oubari, Mohamed, Okoronkwo, Josephine, Reboud-Ravaux, Michèle, Gatell, José Maria, Marquet, Roland, Paillart, Jean-Christophe, Meyerhans, Andreas, Tisné, Carine, Gorelick, Robert J., Mirambeau, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625067/
https://www.ncbi.nlm.nih.gov/pubmed/34835118
http://dx.doi.org/10.3390/v13112312