The Impact of Acquired Genetic Abnormalities on the Clinical Translation of Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSC) are known to acquire chromosomal abnormalities, which range from point mutations to large copy number changes, including full chromosome aneuploidy. These aberrations have a wide-ranging influence on the state of cells, in both the undifferentiated and differentia...

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Detalles Bibliográficos
Autores principales: Keller, Alexander, Spits, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625075/
https://www.ncbi.nlm.nih.gov/pubmed/34831467
http://dx.doi.org/10.3390/cells10113246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625075/
https://www.ncbi.nlm.nih.gov/pubmed/34831467
http://dx.doi.org/10.3390/cells10113246

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