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Direct Interaction of ATP7B and LC3B Proteins Suggests a Cooperative Role of Copper Transportation and Autophagy

Macroautophagy/autophagy plays an important role in cellular copper clearance. The means by which the copper metabolism and autophagy pathways interact mechanistically is vastly unexplored. Dysfunctional ATP7B, a copper-transporting ATPase, is involved in the development of monogenic Wilson disease,...

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Detalles Bibliográficos
Autores principales: Pantoom, Supansa, Pomorski, Adam, Huth, Katharina, Hund, Christina, Petters, Janine, Krężel, Artur, Hermann, Andreas, Lukas, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625360/
https://www.ncbi.nlm.nih.gov/pubmed/34831341
http://dx.doi.org/10.3390/cells10113118