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Direct Interaction of ATP7B and LC3B Proteins Suggests a Cooperative Role of Copper Transportation and Autophagy
Macroautophagy/autophagy plays an important role in cellular copper clearance. The means by which the copper metabolism and autophagy pathways interact mechanistically is vastly unexplored. Dysfunctional ATP7B, a copper-transporting ATPase, is involved in the development of monogenic Wilson disease,...
Autores principales: | Pantoom, Supansa, Pomorski, Adam, Huth, Katharina, Hund, Christina, Petters, Janine, Krężel, Artur, Hermann, Andreas, Lukas, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625360/ https://www.ncbi.nlm.nih.gov/pubmed/34831341 http://dx.doi.org/10.3390/cells10113118 |
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