Abnormal Circulating Maternal miRNA Expression Is Associated with a Low (<4%) Cell-Free DNA Fetal Fraction

The present pilot study investigates whether an abnormal miRNA profile in NIPT plasma samples can explain the finding of a low cell-free DNA (cfDNA) fetal fraction (cfDNAff) in euploid fetuses and non-obese women. Twelve women who underwent neoBona(®) NIPT with a normal fetal karyotype were studied....

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Detalles Bibliográficos
Autores principales: Santoro, Graziano, Lapucci, Cristina, Giannoccaro, Marco, Caporilli, Simona, Rusin, Martina, Seidenari, Anna, Ferrari, Maurizio, Farina, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625387/
https://www.ncbi.nlm.nih.gov/pubmed/34829454
http://dx.doi.org/10.3390/diagnostics11112108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625387/
https://www.ncbi.nlm.nih.gov/pubmed/34829454
http://dx.doi.org/10.3390/diagnostics11112108

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