Microglia-Based Sex-Biased Neuropathology in Early-Stage Alzheimer’s Disease Model Mice and the Potential Pharmacologic Efficacy of Dioscin

Alzheimer’s disease (AD), the most common form of dementia, is characterized by amyloid-β (Aβ) accumulation, microglia-associated neuroinflammation, and synaptic loss. The detailed neuropathologic characteristics in early-stage AD, however, are largely unclear. We evaluated the pathologic brain alte...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Zhou, Qian, Zhang, Jia-He, Wang, Ke-Yong, Saito, Takashi, Saido, Takaomi C., Wang, Xiaoying, Gao, Xiumei, Azuma, Kagaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625413/
https://www.ncbi.nlm.nih.gov/pubmed/34831483
http://dx.doi.org/10.3390/cells10113261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625413/
https://www.ncbi.nlm.nih.gov/pubmed/34831483
http://dx.doi.org/10.3390/cells10113261

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