Quantification of Degradation Products Formed during Heat Sterilization of Glucose Solutions by LC-MS/MS: Impact of Autoclaving Temperature and Duration on Degradation

Heat sterilization of glucose solutions can lead to the formation of various glucose degradation products (GDPs) due to oxidation, hydrolysis, and dehydration. GDPs can have toxic effects after parenteral administration due to their high reactivity. In this study, the application of the F0 concept t...

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Detalles Bibliográficos
Autores principales: Leitzen, Sarah, Vogel, Matthias, Steffens, Michael, Zapf, Thomas, Müller, Christa Elisabeth, Brandl, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625795/
https://www.ncbi.nlm.nih.gov/pubmed/34832903
http://dx.doi.org/10.3390/ph14111121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625795/
https://www.ncbi.nlm.nih.gov/pubmed/34832903
http://dx.doi.org/10.3390/ph14111121

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