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Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

Excess body weight is thought to increase the risk of aggressive prostate cancer (PCa), although the biological mechanism is currently unclear. Body fatness is positively associated with a diminished cellular response to insulin and biomarkers of insulin signalling have been positively associated wi...

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Detalles Bibliográficos
Autores principales: James, Rachel, Dimopoulou, Olympia, Martin, Richard M., Perks, Claire M., Kelly, Claire, Mathias, Louise, Brugger, Stefan, Higgins, Julian P. T., Lewis, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625823/
https://www.ncbi.nlm.nih.gov/pubmed/34822385
http://dx.doi.org/10.3390/metabo11110726