Structure-Activity Relationships of Holothuroid’s Triterpene Glycosides and Some In Silico Insights Obtained by Molecular Dynamics Study on the Mechanisms of Their Membranolytic Action

The article describes the structure-activity relationships (SAR) for a broad series of sea cucumber glycosides on different tumor cell lines and erythrocytes, and an in silico modulation of the interaction of selected glycosides from the sea cucumber Eupentacta fraudatrix with model erythrocyte memb...

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Detalles Bibliográficos
Autores principales: Zelepuga, Elena A., Silchenko, Alexandra S., Avilov, Sergey A., Kalinin, Vladimir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625879/
https://www.ncbi.nlm.nih.gov/pubmed/34822475
http://dx.doi.org/10.3390/md19110604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625879/
https://www.ncbi.nlm.nih.gov/pubmed/34822475
http://dx.doi.org/10.3390/md19110604

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