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Molecular Classification and Interpretation of Amyotrophic Lateral Sclerosis Using Deep Convolution Neural Networks and Shapley Values

Amyotrophic lateral sclerosis (ALS) is a prototypical neurodegenerative disease characterized by progressive degeneration of motor neurons to severely effect the functionality to control voluntary muscle movement. Most of the non-additive genetic aberrations responsible for ALS make its molecular cl...

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Detalles Bibliográficos
Autores principales: Karim, Abdul, Su, Zheng, West, Phillip K., Keon, Matthew, Shamsani, Jannah, Brennan, Samuel, Wong, Ted, Milicevic, Ognjen, Teunisse, Guus, Rad, Hima Nikafshan, Sattar, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626003/
https://www.ncbi.nlm.nih.gov/pubmed/34828360
http://dx.doi.org/10.3390/genes12111754