Signaling through the S1P−S1PR Axis in the Gut, the Immune and the Central Nervous System in Multiple Sclerosis: Implication for Pathogenesis and Treatment

Sphingosine 1-phosphate (S1P) is a signaling molecule with complex biological functions that are exerted through the activation of sphingosine 1-phosphate receptors 1–5 (S1PR1–5). S1PR expression is necessary for cell proliferation, angiogenesis, neurogenesis and, importantly, for the egress of lymp...

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Detalles Bibliográficos
Autores principales: Chatzikonstantinou, Simela, Poulidou, Vasiliki, Arnaoutoglou, Marianthi, Kazis, Dimitrios, Heliopoulos, Ioannis, Grigoriadis, Nikolaos, Boziki, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626013/
https://www.ncbi.nlm.nih.gov/pubmed/34831439
http://dx.doi.org/10.3390/cells10113217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626013/
https://www.ncbi.nlm.nih.gov/pubmed/34831439
http://dx.doi.org/10.3390/cells10113217

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