Calciprotein Particles Link Disturbed Mineral Homeostasis with Cardiovascular Disease by Causing Endothelial Dysfunction and Vascular Inflammation

An association between high serum calcium/phosphate and cardiovascular events or death is well-established. However, a mechanistic explanation of this correlation is lacking. Here, we examined the role of calciprotein particles (CPPs), nanoscale bodies forming in the human blood upon its supersatura...

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Autores principales: Shishkova, Daria K., Velikanova, Elena A., Bogdanov, Leo A., Sinitsky, Maxim Yu., Kostyunin, Alexander E., Tsepokina, Anna V., Gruzdeva, Olga V., Mironov, Andrey V., Mukhamadiyarov, Rinat A., Glushkova, Tatiana V., Krivkina, Evgenia O., Matveeva, Vera G., Hryachkova, Oksana N., Markova, Victoria E., Dyleva, Yulia A., Belik, Ekaterina V., Frolov, Alexey V., Shabaev, Amin R., Efimova, Olga S., Popova, Anna N., Malysheva, Valentina Yu., Kolmykov, Roman P., Sevostyanov, Oleg G., Russakov, Dmitriy M., Dolganyuk, Viatcheslav F., Gutakovsky, Anton K., Zhivodkov, Yuriy A., Kozhukhov, Anton S., Brusina, Elena B., Ismagilov, Zinfer R., Barbarash, Olga L., Yuzhalin, Arseniy E., Kutikhin, Anton G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626027/
https://www.ncbi.nlm.nih.gov/pubmed/34830334
http://dx.doi.org/10.3390/ijms222212458