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Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma

Frequent relapses and therapeutic resistance make the management of glioblastoma (GBM, grade IV glioma), extremely difficult. Therefore, it is necessary to develop new pharmacological compounds to be used as a single treatment or in combination with current therapies in order to improve their effect...

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Detalles Bibliográficos
Autores principales: Colapietro, Alessandro, Rossetti, Alessandra, Mancini, Andrea, Martellucci, Stefano, Ocone, Giuseppe, Pulcini, Fanny, Biordi, Leda, Cristiano, Loredana, Mattei, Vincenzo, Delle Monache, Simona, Marampon, Francesco, Gravina, Giovanni Luca, Festuccia, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626029/
https://www.ncbi.nlm.nih.gov/pubmed/34832864
http://dx.doi.org/10.3390/ph14111082