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Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma
Frequent relapses and therapeutic resistance make the management of glioblastoma (GBM, grade IV glioma), extremely difficult. Therefore, it is necessary to develop new pharmacological compounds to be used as a single treatment or in combination with current therapies in order to improve their effect...
Autores principales: | Colapietro, Alessandro, Rossetti, Alessandra, Mancini, Andrea, Martellucci, Stefano, Ocone, Giuseppe, Pulcini, Fanny, Biordi, Leda, Cristiano, Loredana, Mattei, Vincenzo, Delle Monache, Simona, Marampon, Francesco, Gravina, Giovanni Luca, Festuccia, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626029/ https://www.ncbi.nlm.nih.gov/pubmed/34832864 http://dx.doi.org/10.3390/ph14111082 |
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