Enhancement of the Local CD8(+) T-Cellular Immune Response to Mycobacterium tuberculosis in BCG-Primed Mice after Intranasal Administration of Influenza Vector Vaccine Carrying TB10.4 and HspX Antigens

BCG is the only licensed vaccine against Mycobacterium tuberculosis (M.tb) infection. Due to its intramuscular administration route, BCG is unable to induce a local protective immune response in the respiratory system. Moreover, BCG has a diminished ability to induce long-lived memory T-cells which...

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Detalles Bibliográficos
Autores principales: Vasilyev, Kirill, Shurygina, Anna-Polina, Zabolotnykh, Natalia, Sergeeva, Mariia, Romanovskaya-Romanko, Ekaterina, Pulkina, Anastasia, Buzitskaya, Janna, Dogonadze, Marine Z., Vinogradova, Tatiana I., Stukova, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626046/
https://www.ncbi.nlm.nih.gov/pubmed/34835204
http://dx.doi.org/10.3390/vaccines9111273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626046/
https://www.ncbi.nlm.nih.gov/pubmed/34835204
http://dx.doi.org/10.3390/vaccines9111273

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