Mechanical Stretch Induces Annulus Fibrosus Cell Senescence through Activation of the RhoA/ROCK Pathway

BACKGROUND: Intervertebral disc is responsible for absorbing and transmitting mechanical compression. Under physiological conditions, the peripheral annulus fibrosus (AF) cells are subjected to different magnitudes of transverse mechanical stretch depending on the swelling of the central nucleus pul...

Descripción completa

Detalles Bibliográficos
Autores principales: Ning, Li, Gao, Lei, Zhang, Fan, Li, Xiaoxiao, Wang, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626192/
https://www.ncbi.nlm.nih.gov/pubmed/34840974
http://dx.doi.org/10.1155/2021/5321121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626192/
https://www.ncbi.nlm.nih.gov/pubmed/34840974
http://dx.doi.org/10.1155/2021/5321121

Ejemplares similares