β(2)-Adrenoceptor Activation Stimulates IL-6 Production via PKA, ERK1/2, Src, and Beta-Arrestin2 Signaling Pathways in Human Bronchial Epithelia

OBJECTIVE: β(2)-Adrenoceptor agonists are widely used to treat asthma because of their bronchial-dilation effects. We previously reported that isoprenaline, via the apical and basolateral β(2)-adrenoceptor, induced Cl(−) secretion by activating cyclic AMP (cAMP)-dependent pathways in human bronchial...

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Detalles Bibliográficos
Autores principales: Zhang, Rui-Gang, Niu, Ya, Pan, Ke-Wu, Pang, Hao, Chen, Chun-Ling, Yip, Chung-Yin, Ko, Wing-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Beta-2-Adrenoceptors in Human Bronchial Epithelia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626360/
https://www.ncbi.nlm.nih.gov/pubmed/34725715
http://dx.doi.org/10.1007/s00408-021-00484-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626360/
https://www.ncbi.nlm.nih.gov/pubmed/34725715
http://dx.doi.org/10.1007/s00408-021-00484-0

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