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A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division

The PKCε-regulated genome protective pathway provides transformed cells a failsafe to successfully complete mitosis. Despite the necessary role for Aurora B in this programme, it is unclear whether its requirement is sufficient or if other PKCε cell cycle targets are involved. To address this, we de...

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Detalles Bibliográficos
Autores principales: Martini, Silvia, Davis, Khalil, Faraway, Rupert, Elze, Lisa, Lockwood, Nicola, Jones, Andrew, Xie, Xiao, McDonald, Neil Q., Mann, David J., Armstrong, Alan, Ule, Jernej, Parker, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626422/
https://www.ncbi.nlm.nih.gov/pubmed/34836941
http://dx.doi.org/10.1038/s41467-021-27189-5