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A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division
The PKCε-regulated genome protective pathway provides transformed cells a failsafe to successfully complete mitosis. Despite the necessary role for Aurora B in this programme, it is unclear whether its requirement is sufficient or if other PKCε cell cycle targets are involved. To address this, we de...
Autores principales: | Martini, Silvia, Davis, Khalil, Faraway, Rupert, Elze, Lisa, Lockwood, Nicola, Jones, Andrew, Xie, Xiao, McDonald, Neil Q., Mann, David J., Armstrong, Alan, Ule, Jernej, Parker, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626422/ https://www.ncbi.nlm.nih.gov/pubmed/34836941 http://dx.doi.org/10.1038/s41467-021-27189-5 |
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