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Polygenic risk scores across the extended psychosis spectrum

As early detection of symptoms in the subclinical to clinical psychosis spectrum may improve health outcomes, knowing the probabilistic susceptibility of developing a disorder could guide mitigation measures and clinical intervention. In this context, polygenic risk scores (PRSs) quantifying the add...

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Detalles Bibliográficos
Autores principales: Smigielski, Lukasz, Papiol, Sergi, Theodoridou, Anastasia, Heekeren, Karsten, Gerstenberg, Miriam, Wotruba, Diana, Buechler, Roman, Hoffmann, Per, Herms, Stefan, Adorjan, Kristina, Anderson-Schmidt, Heike, Budde, Monika, Comes, Ashley L., Gade, Katrin, Heilbronner, Maria, Heilbronner, Urs, Kalman, Janos L., Klöhn-Saghatolislam, Farahnaz, Reich-Erkelenz, Daniela, Schaupp, Sabrina K., Schulte, Eva C., Senner, Fanny, Anghelescu, Ion-George, Arolt, Volker, Baune, Bernhard T., Dannlowski, Udo, Dietrich, Detlef E., Fallgatter, Andreas J., Figge, Christian, Jäger, Markus, Juckel, Georg, Konrad, Carsten, Nieratschker, Vanessa, Reimer, Jens, Reininghaus, Eva, Schmauß, Max, Spitzer, Carsten, von Hagen, Martin, Wiltfang, Jens, Zimmermann, Jörg, Gryaznova, Anna, Flatau-Nagel, Laura, Reitt, Markus, Meyers, Milena, Emons, Barbara, Haußleiter, Ida Sybille, Lang, Fabian U., Becker, Thomas, Wigand, Moritz E., Witt, Stephanie H., Degenhardt, Franziska, Forstner, Andreas J., Rietschel, Marcella, Nöthen, Markus M., Andlauer, Till F. M., Rössler, Wulf, Walitza, Susanne, Falkai, Peter, Schulze, Thomas G., Grünblatt, Edna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626446/
https://www.ncbi.nlm.nih.gov/pubmed/34836939
http://dx.doi.org/10.1038/s41398-021-01720-0