Transcriptional responses of skeletal stem/progenitor cells to hindlimb unloading and recovery correlate with localized but not systemic multi-systems impacts

Disuse osteoporosis (DO) results from mechanical unloading of weight-bearing bones and causes structural changes that compromise skeletal integrity, leading to increased fracture risk. Although bone loss in DO results from imbalances in osteoblast vs. osteoclast activity, its effects on skeletal ste...

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Detalles Bibliográficos
Autores principales: Booker, Cori N., Haga, Christopher L., Boregowda, Siddaraju V., Strivelli, Jacqueline, Phinney, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626488/
https://www.ncbi.nlm.nih.gov/pubmed/34836964
http://dx.doi.org/10.1038/s41526-021-00178-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626488/
https://www.ncbi.nlm.nih.gov/pubmed/34836964
http://dx.doi.org/10.1038/s41526-021-00178-0

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