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Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells

Ovarian cancers are among the fatal malignancies affecting women globally, mainly due to their metastatic and chemoresistant nature. In this study, we report a potent curcumin derivative ST09 effective against ovarian cancers. Prior in-vitro studies with ST09 drug showed cytotoxicity in tumorigenic...

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Detalles Bibliográficos
Autores principales: Ravindran, Febina, Koroth, Jinsha, Manjunath, Meghana, Narayan, Suchitra, Choudhary, Bibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626492/
https://www.ncbi.nlm.nih.gov/pubmed/34837026
http://dx.doi.org/10.1038/s41598-021-02454-1