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Stroke subtype-dependent synapse elimination by reactive gliosis in mice

The pathological role of reactive gliosis in CNS repair remains controversial. In this study, using murine ischemic and hemorrhagic stroke models, we demonstrated that microglia/macrophages and astrocytes are differentially involved in engulfing synapses in the reactive gliosis region. By specifical...

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Detalles Bibliográficos
Autores principales: Shi, Xiaojing, Luo, Longlong, Wang, Jixian, Shen, Hui, Li, Yongfang, Mamtilahun, Muyassar, Liu, Chang, Shi, Rubing, Lee, Joon-Hyuk, Tian, Hengli, Zhang, Zhijun, Wang, Yongting, Chung, Won-Suk, Tang, Yaohui, Yang, Guo-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626497/
https://www.ncbi.nlm.nih.gov/pubmed/34836962
http://dx.doi.org/10.1038/s41467-021-27248-x