Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

Several effective SARS-CoV-2 vaccines are currently in use, but effective boosters are needed to maintain or increase immunity due to waning responses and the emergence of novel variants. Here we report that intranasal vaccinations with adenovirus 5 and 19a vectored vaccines following a systemic pla...

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Detalles Bibliográficos
Autores principales: Lapuente, Dennis, Fuchs, Jana, Willar, Jonas, Vieira Antão, Ana, Eberlein, Valentina, Uhlig, Nadja, Issmail, Leila, Schmidt, Anna, Oltmanns, Friederike, Peter, Antonia Sophia, Mueller-Schmucker, Sandra, Irrgang, Pascal, Fraedrich, Kirsten, Cara, Andrea, Hoffmann, Markus, Pöhlmann, Stefan, Ensser, Armin, Pertl, Cordula, Willert, Torsten, Thirion, Christian, Grunwald, Thomas, Überla, Klaus, Tenbusch, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626513/
https://www.ncbi.nlm.nih.gov/pubmed/34836955
http://dx.doi.org/10.1038/s41467-021-27063-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626513/
https://www.ncbi.nlm.nih.gov/pubmed/34836955
http://dx.doi.org/10.1038/s41467-021-27063-4

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