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Quinacrine-CASIN combination overcomes chemoresistance in human acute lymphoid leukemia

Chemoresistance posts a major hurdle for treatment of acute leukemia. There is increasing evidence that prolonged and intensive chemotherapy often fails to eradicate leukemic stem cells, which are protected by the bone marrow niche and can induce relapse. Thus, new therapeutic approaches to overcome...

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Detalles Bibliográficos
Autores principales: Wu, Limei, Chatla, Srinivas, Lin, Qiqi, Chowdhury, Fabliha Ahmed, Geldenhuys, Werner, Du, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626516/
https://www.ncbi.nlm.nih.gov/pubmed/34836965
http://dx.doi.org/10.1038/s41467-021-27300-w