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Collagen’s primary structure determines collagen:HSP47 complex stoichiometry

Collagens play important roles in development and homeostasis in most higher organisms. In order to function, collagens require the specific chaperone HSP47 for proper folding and secretion. HSP47 is known to bind to the collagen triple helix, but the exact positions and numbers of binding sites are...

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Detalles Bibliográficos
Autores principales: Abraham, Elena T., Oecal, Sinan, Mörgelin, Matthias, Schmid, Philipp W.N., Buchner, Johannes, Baumann, Ulrich, Gebauer, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626583/
https://www.ncbi.nlm.nih.gov/pubmed/34487762
http://dx.doi.org/10.1016/j.jbc.2021.101169