A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease

Nonalcohol-associated fatty liver disease (NAFLD) is characterized by excessive hepatic accumulation of fat that can progress to steatohepatitis, and currently, therapeutic options are limited. Using a high-fat diet (HFD) mouse model of NAFLD, we determined the effects of the synthetic retinoid, AC2...

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Detalles Bibliográficos
Autores principales: Tang, Xiao-Han, Melis, Marta, Lu, Changyuan, Rappa, Andrew, Zhang, Tuo, Jessurun, Jose, Gross, Steven S., Gudas, Lorraine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626588/
https://www.ncbi.nlm.nih.gov/pubmed/34688661
http://dx.doi.org/10.1016/j.jbc.2021.101331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626588/
https://www.ncbi.nlm.nih.gov/pubmed/34688661
http://dx.doi.org/10.1016/j.jbc.2021.101331

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