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DNA crosslinking and recombination‐activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia

BACKGROUND: Abnormal alternative splicing is frequently associated with carcinogenesis. In B‐cell acute lymphoblastic leukemia (B‐ALL), double homeobox 4 fused with immunoglobulin heavy chain (DUX4/IGH) can lead to the aberrant production of E‐26 transformation‐specific family related gene abnormal...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Cheng, Nuo, Li, Zhihui, Bai, Ling, Fang, Chengli, Li, Yuwen, Zhang, Weina, Dong, Xue, Jiang, Minghao, Liang, Yang, Zhang, Sujiang, Mi, Jianqing, Zhu, Jiang, Zhang, Yu, Chen, Sai‐Juan, Zhao, Yajie, Weng, Xiang‐Qin, Hu, Weiguo, Chen, Zhu, Huang, Jinyan, Meng, Guoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626599/
https://www.ncbi.nlm.nih.gov/pubmed/34699692
http://dx.doi.org/10.1002/cac2.12234