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BX-795 inhibits neuroblastoma growth and enhances sensitivity towards chemotherapy

High-risk neuroblastoma (NB) represents a major clinical challenge in pediatric oncology due to relapse of metastatic, drug-resistant disease, and treatment-related toxicities. An analysis of 1235 primary NB patient dataset revealed significant increase in AKT1 and AKT2 gene expression with cancer s...

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Detalles Bibliográficos
Autores principales: Chilamakuri, Rameswari, Rouse, Danielle C., Yu, Yang, Kabir, Abbas S., Muth, Aaron, Yang, Jianhua, Lipton, Jeffery M., Agarwal, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626612/
https://www.ncbi.nlm.nih.gov/pubmed/34823094
http://dx.doi.org/10.1016/j.tranon.2021.101272